> "new, man-made chemical compounds that has never existed before"

GMO cultivars usually do not contain new, man-made chemical compounds.

For example, Golden Rice contain beta carotene (occurs naturally in e.g. carrots).

The virus resistant Hawaiian Rainbow Papaya contains a protein from the virus' capsid, effective "vaccinating" the plants, resulting in virus resistance.

Bt Cotton contains a chemical from Bacillus thuringiensis, a common bacterium in soils, that is harmful to pest insects.