-Write good, semantic HTML, and use alt tags correctly
-Don't overwrite browser defaults for scrolling, tabbing, etc (even if it's "hot design")
-Don't rely purely on color to convey information
-Use ARIA attributes where you can if you're building an application
Some harder stuff that is really still worth it:
-Send your media out for subtitling/transcription (remarkably inexpensive)
-Actually test your site with some disabled individuals, or at least have a go yourself with the NoCoffee Chrome extension to simulate certain visual difficulties