Depression's Evolutionary Roots
scientificamerican.com
scientificamerican.com
http://en.wikipedia.org/wiki/Depressive_realism
is to be expected rather than puzzling.
http://www.amazon.com/Touched-Fire-Manic-Depressive-Artistic...
and co-author of the definitive text on manic-depressive illness
http://www.amazon.com/Manic-Depressive-Illness-Disorders-Rec...
has thought out loud in her writings over the years about whether treatments for depression that help suffering people may also deprive society of creative output. Her current thinking on the issue--and she takes lithium herself every day--is that the best-evidenced mood-stabilizing treatments for mood disorders are helpful to patients and increase rather than decrease their ability to contribute useful work product to society. Her co-author, Frederick K. Goodwin, M.D., is still deeply skeptical of some antidepressant medications (e.g., the selective serotonin reuptake inhibitors) because of their capacity for inducing mania in many bipolar patients.
Depression still exists due to the evolutionary reasons described in the article. However, since depression is caused by certain reactions in the brain, other things can cause depression.
Just a guess though.
The points in this article sound logical to me and also useful. Dismissing them as "pure speculation" does not seem justified.