Though there may be bulletproof ways for criminals to bypass such automatic scanning. For example, I've heard of criminals creating two versions of their site: One, a harmless site, that you get if you type in the domain name cold, and then a criminal one, that you only get if you have the right referrer header or query string. Which makes it difficult or impossible for an outside entity to see the illegal content without access to the spam email, referring site, or what have you.
I don't know much about ngrok, but I take it you can tunnel SSL over it such that it's impossible for ngrok to inspect the contents of your traffic. Which would rule another viable strategy: Monitor traffic for suspicious keywords, thus bypassing the cloaking techniques described above.
Any other techniques for automated flagging that I might be missing? Maybe some kind of content-agnostic traffic analysis that spots a likely spam fingerprint, e.g. certain chronological traffic patterns?