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"Hey bob, here is a link to a folder on my machine - can you upload that those [random file types] you want me to look at?"

or

"non-tech wife needs to get this file to our home machine, she can use my link to /home/put/ to send this to my home machine from her work"

How is a non-technical person supposed to execute a POST request with an attached file to Knod?

At a guess, using a browser with a file upload form downloaded from the same place where the file will go.

That's fair, although it goes beyond what Knowd provides.

Got the idea while working through the React tutorial some time ago. Thought a zero config server that responds to all of the HTTP verbs would make a nice tool for front end prototyping.

I extended Python SimpleHTTPServer as a data store server for some web games and also as a cross-site XML server for said games. Knod would fit that niche just fine.