For example, if you are negotiating your salary for a first-time software engineering gig and open with $500k, the other side is likely to say something like, "There is absolutely no way we can do that. We would like to offer you $75k." If you're offer gets wiped off the table, your anchor has absolutely no power in the negotiation.
So go high (or low, if you're on the other side of the table), but don't be too extreme.
The gist of the answer was "we feel that you are in range of [some job level/position] but only the very senior people in that department are paid in the range you mentioned as your requirement."
So they decided not to spend any more time with me because of the mismatch of salary and their perception of my experience level so far.
So I tried something and it works a lot better: I ask them for a concrete date/time we can meet again for a date. I give zero importance to their number. Qualitatively, I think most girls are "shocked" and not used to someone telling them their phone number is completely irrelevant.
therefore if you're an engineer and the typical job is 100 thousand, ask me for 120 if you want to play this game. It is unlikely this would shut down the conversation though it may send up a warning flag.
Anything over that and I don't see a point to continue the conversation. I wonder if you are clueless about your value or if you are a diva who will cause too many headaches later. You can't take it back either.