If AdBlock becomes a big enough problem, publishers will create "unskippable" ads with current technology. HTML doesn't really change that. It's always been a cat and mouse with ad blockers.
I could "protect" the copyright on my site's content with a trivial bit of a javascript, and you would arguably be circumventing it with your ad blocker.
(To be clear: I think the DMCA anti-circumvention provisions are terrible policy.)