Cormac McCarthy writes everything on a typewriter that cost him $50 in 1964 [1]. The novel, A Confederacy of Dunces was written by hand [2]. So I guess this means that when it comes to writing, especially writing fiction, the man and his mind are what matters.
[1] http://artsbeat.blogs.nytimes.com/2009/12/04/cormac-mccarthy...
[2] http://www.broadwayworld.com/article/John-Kennedy-Tooles-A-C...