So, I wouldn't use this box because it doesn't ECC Memory (http://en.wikipedia.org/wiki/ECC_memory). Google some years ago did a study on DRAM errors in the wild, in order to determine if there was an actual need for ECC in modern datacenters / distributed computing applications (http://www.cs.utoronto.ca/~bianca/papers/sigmetrics09.pdf). The short summary was that yes, they did need it.
Given that the processors (http://ark.intel.com/products/64903/Intel-Core-i5-3427U-Proc...) that are on these NUCs don't support ECC, I would probably avoid these units for any real workload.
It bums me a out a little bit that there is only a 1G fabric on these, when each board has two mini-PCIe ports, which is at 2Gbit/sec, and make a ring topology out of them, or using a PCIe switch. Another interesting approach could have been a usb 3 fabric.