"Hi. Thanks for applying. Sorry I can't seem to open your CV. Could you please resend it to me in MS Word?"
When applying for jobs in Sweden I have not had any problems using a PDF.
Lesson: always bring lots of copies of your resume to the interview: I thought ten was sufficient, and I was almost wrong. Also: the tech skill of HR has nothing to do with the tech skill of engineers in a medium-to-large business.
I feel like the whole job search dance is about finding the right fit, not just doing whatever it takes to shoehorn oneself through the door. MS Word only is a huge red flag. I feel like it sends a strong message as to what the culture is like at the company. On the other hand, troff only and I would be curious. I'd at least want to look at the people who made that request.