I think HTTP request and response headers make a great example.
You read a raw stream of bytes line by line (8-bit fixed), and split on newlines.
In this protocol we know that each string is "latin-1", so we can extract and decode each header with this encoding. At virtually zero cost, because we don't copy, or transcode the actual string data.
And what's more, we stay true to the protocol. These headers were never unicode-encoded (any variant), so it is awkward to suddenly have unicode strings to deal with in the rest of the program.
The alternative would be bytes, but in Python 3, those are simply impossible to work with as strings.
Why is Python 3 unpopular? It's because it does not really advance Python as a language. It's a bit cleaner around the edges, but the cost was very high for very little gain.