I barely use jquery at all and build rather large JS applications. YMMV
http://paulhammant.com/2012/03/03/replacing-jquery-with-angu...
"Don’t even use jQuery. Don’t even include it. It will hold you back. And when you come to a problem that you think you know how to solve in jQuery already, before you reach for the $, try to think about how to do it within the confines the AngularJS. If you don’t know, ask! 19 times out of 20, the best way to do it doesn’t need jQuery and to try to solve it with jQuery results in more work for you."