Those are some pretty cool projects. This sort of thing really needs to be supported natively in the browsers and written into the ECMAScript standards, though. It looks like what both Browserify and Bower are doing is basically a macro expansion that outputs regular Javascript, which is interesting, but really shouldn't be necessary.

Basically the current state is that everyone knows that HTML/CSS/JS sucks (by sucks I mean not adequately productive to work in, relative to the feature demands of modern web applications), so we're building languages that compile to them so that we don't have to write them directly. JS is becoming like the assembly language of the web. Some cool stuff has come out of that, but it doesn't mean we should give up on trying to make HTML/CSS/JS better. They were designed to be written by humans, so we shouldn't need to compile to them in order to be productive.