Sure. We're building a single page webapp here at http://izooble.com. Our frontend is Model-View-Nothing with React for the view and TypeScript for everything else. We build with gulp, and avoid browserify because it makes debugging more difficult. Therefore, we generate a debug and a production build: the production build simply concats all generated JS, and the debug build keeps the separate JS files with source maps back to the .ts sources. We autogenerate the index.html.

Some of us code TypeScript in Visual Studio, which is awesome. Many just use a text editor and `gulp watch`, though, which works remarkably good as well. I wish there was good TypeScript IDE support on other platforms than Windows. The entire team has previous experience that makes them think strongly in terms of classes and object. TypeScript is a very natural fit for a team like this, and made us productive very fast. Prototypal inheritance, not so sure.

On the backend, we do C#, hosted on Linux with Mono (we have devs running Linux, Mac and Windows, we're just as cross-platform as your average Python shop). We use ServiceStack v3 for the API and PostgreSQL for data. We heavily rely on stored procedures and Postgres-specific features (such as returning cursor sets instead of gigantic joins) for making the backend very lean and simple.

We use Docker for running stuff locally and in production. Our designers just run the backend docker containers locally with a single click (in Vagrant). They never installed Mono or Postgres anywhere.

Is that what you wanted to know?