Some good comments here that I feel like implementing
@ColonelPanic001 : dark cube, overhead lights off, monitor at minimum brightness
@jisaacstone : large monitor, big font, keep it far away. Relax instead of leaning in toward the screen. I am often mentally tired at the end of day but no eye strain.
@a8da6b0c91d : get sunlight
@xbonez : try http://justgetflux.com/
@djb_hackernews : Personal experience on why taking timely care is important