Of those, |, @, #, ^, {, } and ~ are all keys that you need shift for on US Qwerty keyboards, so I imagine that the typing experience for those is relatively comparable.
(I do really miss the days when Mac keyboards had the weird symbol they use for "alt" in menus on the key.)
In the past, I've bought US Mac keyboards just for the #, or switched the keyboard layout in software to US.
Must be annoying to have to press shift to get those symbol chars while you're coding, eh?
Honestly no. It's all muscle memory for me, I don't think about it any more than I think about typing capital letters.
I just think people will criticise their local layout no matter what. I use both a French AZERTY and a Québec QWERTY everyday (at work/home) and I think they are simply equally good for both typing French and for coding. The Québec keyboard (maybe actually Canadian multilingual or something) might have an edge because it more easily allows typing accented letters in uppercase, but on the other hand it doesn't let me type the € sign, so...