Most of the time when I hear designers complaining about Android fragmentation they are really just using "fragmentation" as a scapegoat to bemoan they fact that they can't just create a very small set (1-3) of universal "pixel perfect" mockups and ship those off as a PSD to a developer as the end-all, be-all "visual spec". They have to worry about things like how different parts of the app should scale as more real estate is made available, really understand DPI (I've met more than a few designers who shockingly don't really grasp DPI scaling), etc. Some designers are awesome at this and welcome the challenges (and benefits!) that "responsive layout" brings with it, but a lot of them (most of them, in my personal experience) just want to punt on all that shit.