https://www.gnu.org/software/guile/gnu-guile-projects.html
That being said, most languages need some form of dependency management, and this story has yet to see an ending in Guile. People continue work on one called Guildhall, but it is not yet complete.
http://wingolog.org/archives/2011/07/04/guile-2-0-2-building...
I tried deploying on my Arch Linux laptop, and encountered some issues. I also thought it would be cool to try Guile and GNOME for quick apps, but without dependency managers and incomplete documentation, it is hard for me as I am, if I can toot my own horn, a low-intermediate Linux user and a very novice Scheme student.
So long story short: toolchain and documentation are not there yet. I continue to hope because it is still cool.
Also, check this blog. I and others mentioned it. It is very cool and gives you very deep technical insight from a Guile maintainer into all the hard work being put into its core improvements.
In short, it is no Lua (or really Lua+LuaJIT), but it might be there one day.