Yes, but the GP was proposing using OPT as a founder visa. In that case, you need to get your own startup to sponsor your H1B; that's pretty hard to do. I imagine you'd have to offer the market salary for "startup CEO" (whatever that is), post an ad for 30 days and then prove that you couldn't find an American to take that job (this is usually the process for regular H1B employees).

EDIT: It seems you can get a H1B where you work for your own company, it just needs special approval (there's a link to it earlier in this thread).