I used to play it on a 90MHz Pentium with 48MB of RAM, running Windows NT4, and let me tell you, it did not run well.
I remember there being this one mission where you have to survive for a fixed amount of time (10min? 15min?), and on this machine it lasted more like half an hour. Also reminds you how they accounted for time in those days.
Diablo (the first) with the Hellfire expansion ran smooth as butter on the same machine. I also remember trying to do Python and Java on that machine, didn't go over to well either, although Python wasn't too bad.