I'm still on an earlier version of TypeScript, so I don't know if later versions have fixed this. We ran into trouble when creating knockout view models in type script. Basically, TypeScript was losing track of 'this', and the trick of using var self=this in the the "constructor" wasn't valid. We made it work, but it wasn't pretty and it certainly wasn't idiomatic typescript.

Basically the problem was that we were trying to write TypeScript like we were writing C#, instead of treating typescript like a layer on top of JavaScript.