Django requires multiple processes, which makes sharing things like connections quite difficult. That is not sane.
An addiction to globally shared state across threads multiplies race conditions and scaling problems, even if the GIL magically goes away. If you are incapable of using even processes effectively then I really fear for you when you have to scale out horizontally.
I'd say this more nicely if I could think of any way, but you don't know what you're talking about and you should read up before you begin talking about it again. It looks bad and you might mislead someone.