At most, it means you're coasting with no power assist for steering or brakes -- you'll need some extra braking distance, but that's what the shoulder is for, and it'll take a bit more than the usual effort to turn the wheel, which means that getting
onto the shoulder, especially if you're in a middle lane when all this goes wrong, is going to need to be smartly done.
Taken all together, the impression I get is of a problem in driving skill that's roughly as difficult as a blown tire at highway speeds -- possibly a bit easier, actually, considering the deleterious effect a blown tire has on steering control. An alert and competent driver should be able to handle either situation without posing a deadly danger to herself or anyone else.
The same, I think, cannot reasonably be said of uncommanded acceleration. With a blown tire or a failed ECU, all you have to do is use your ordinary driving controls to get off the freeway and bring the vehicle to a safe stop. With a throttle stuck wide open, you are suddenly a race car driver, only you're neither in a race car, nor in a race. You can't bring the vehicle to a stop with the ordinary driving controls, at least two of which -- the accelerator and the brake -- are no longer responding properly or at all, which is itself frightening and disorienting to the driver. In order to bring the vehicle to a stop, the driver must shut off the engine with the key, at which point the problem reduces to our failed-ECU worst case above, just with some more speed to burn off.
But there is no circumstance, in either the normal driving regime or even any other abnormal one, where turning off a moving car is a proper or safe response to any situation, which is why almost no driver has ever given the slightest thought to doing so -- and when your car's speeding up past ninety all of a sudden, and you're not telling it to, is maybe not the best time to be thinking up new ways to interact with your car that you've never thought of before. At a guess, I'd say some people whose Toyotas ran away on them were able to come up with the idea in time, and they mostly survived. Others ran out of time before they thought of it, and those unlucky souls mostly died.