To generate the final executables, you'll end up hacking together some shell scripts or the like, at least if you do this on a regular basis.
Both points together: an automated asset pipeline and an easy-to-use build tool is included.
+1 for the data storage part, i'd love to hear some deeper thoughts in the github issues part...
about the chosen technologies: these are my preferences. After spreading my app skeleton idea I expect similar stuff to emerge for other personal preferences. But finally: one of my main goals of spreading the word here is to bring the idea of node-webkit to the folks, since this is an awesome open source project and could use some more helping hands.