For example the OS desktop metaphors could finally be taken to the next level. Files, recycle bins, folders these were mapped concepts in the 80s to try to transfer the office to a 2D computer screen.
But now we can simulate a true desktop. Imagine you enter a room, a nice wooden desk in front of you. On the desk are documents that could be web pages videos word docs anything. You touch it and a floating screen appears to display contents. To your right is an infinite capacity filing cabinet. A trash bin under the desk. Its like the real world but without the limits of the real world.
Another interesting effect is memory. I remember reading somewhere that in ancient times they would memorize lots of data by imagining walking through a house. As you walk you would place relate objects like a closet to the item you want to remember. In this way you memorize the data and its order. This is where the phrase "in the first place...and the second place..." came from.
And its something I've noticed in real life. My desk looks like a mess except to me. There's a order to it I understand and I can find things. A similar thing happens with the mess of icons on my desktop. I can often find something because I know I put it in some folder on some place on the desktop. But in both the real desktop and my windows desktop I sometimes need help finding things and use the search tool.
The VR desktop can be the best of both worlds. It allows that natural chaotic organization I do with my real world desktop. But a floating search box can appear anytime to help me.