See this thread on the Cap'n Proto mailing list for some idea of how well Python does on this benchmark:
https://groups.google.com/forum/#!topic/capnproto/BDpV6WEG5B...
https://groups.google.com/forum/#!topic/capnproto/BDpV6WEG5B...
What's more interesting to me is comparing it to other Python serialization libraries. I've been meaning to update the benchmarks with some popular ones (msgpack, thrift, and the built-in json module are at the top of my list). If there's some interest, I'll go ahead and post it to HN when I'm done.