I don't see a reason for these useless and throwing life away experiences if the purpose is just making the astronauts used to isolation. I kind of get it if it's to study something psychological, but we have so many prisoners in almost the same conditions...
After the moon, everything is just too far away to travel. We can study Mars very well with the robot approach. We're just throwing astronauts life away for our stupid need of putting Men in Mars, which I dare say is utterly pointless.