One language I'm really excited about for scientific computing though is Julia. From a language-design perspective, it's beautiful. It was actually thought out rather than kludged together. I've been trying to gradually use it more and more for my research, but the only problem I've found so far is the large mental context-switch I make going from my usual languages to Julia. It's hard to tell what Julia code will be the most performant because there's many ways of doing the same task. I saw someone in the comments on this page mention that you can hand-tune the LLVM generated output within the REPL itself. I imagine this would be very useful if I can get around to learning it (anyone know a good tutorial?)