If you think 'modelling the entire milky way' is an average use case you don't know very much about graphics or game engines, and you should stop extrapolating based on your horribly inadequate knowledge in order to draw faulty conclusions. Again, I have end-users building games and other types of software that are using 64-bit integers
right now and have told me they actually need 64 bits of precision. In one case they were actually using pairs of 64-bit integers for 128 bits of precision.
For your contrived galaxy example, one thing you need to realize is that value ranges aren't the only thing that matters; value precision is just important, and variable precision is an absolute trainwreck in game development scenarios because it means that your game's physics are nondeterministic (due to precision variance depending on where you are). This is a real problem that affects real games. EVE Online happens to simulate a massive galaxy and massive solar systems, and it uses integers to represent coordinates precisely for this reason.
So crypto needs '256 bit integers' (why 256? why not 512? 2048? 4096?), thus it's okay that dart only offers 53 bits of integer precision, and somehow 64 bits wouldn't be better? Does your CPU have 256-bit integer registers? Last I checked, most integer registers only go up to 64 or 128 bits, and the registers bigger than that are for SIMD - i.e. they contain multiple integers, not one big one. I'm not even demanding that Dart implement arbitrary-precision integer arithmetic here - just actually get 64 bit integer arithmetic right, since VIRTUALLY EVERY real programming environment's VM offers it natively to begin with [0]. If you still insist that nothing less than arbitrary precision integer values are sufficient for crypto, then fine - what about 64-bit hashing algorithms (real; used in production)? What about applications that need to do I/O against files/buffers larger than 4GB? What about applications that need to do graphics rendering against image surfaces larger than 4GB? What about audio editing software that needs to operate on long audio recordings larger than 4GB? When 32-bit unix timestamps overflow in 2036, will 64-bit integers still be unimportant?
These are all real use cases. If you ignore them all and still argue that 64 bit integers don't matter, you don't seem to have the ability to imagine software beyond your experience.
[0] Yes, there are a few scripting runtimes without 64-bit integer values built-in. They are all insufficient for anything resembling numeric computation.