My main job currently involves maintaining and developing a huge code base in Perl including three websites (soon to expand to much more). Perl just works. I thoroughly enjoy coding in it. I've not spent too much time optimizing and testing code though. mod_perl is pretty fast in itself (using Apache).
That being said Perl certainly lacks the in-built features which would make meta programming a quick and easy job. Yes, I still have to start using Moose. Perhaps in 2014!
Happy 26th Birthday Perl! Without you, I wouldn't have a job!