Good points, and you're right that Upworthy is an engine for viral political content, which I find very interesting.
You call it "manipulative slime," but I'm still undecided on the morality of it. On the one hand, the manipulative aspect is incredibly annoying, and I avoid clicking on Upworthy links basically out of spite. On the other hand, is this worse or better than using viral marketing tactics to sell a product? What if Upworthy manages to get hundreds of thousands of people to share an informative video on a civil rights issue that you find to be of pressing importance?
Viewed through this lens, Upworthy is essentially analogous to viral vector gene therapy for the hivemind. Is this inherently evil? Do the ends justify the means? I don't know, but it would be an interesting discussion to have.