Has anything developed resistance to regular household bleach?
http://www.eurekalert.org/pub_releases/2008-11/cp-hhb110708....
"The researchers found that hypochlorous acid, the active ingredient in bleach, causes the unfolding of proteins in bacteria in much the same was that heat stress or fever does. Those denatured proteins then clump together irreversibly into a mass in living cells, similar to what happens to proteins when you boil an egg, according to the researchers.
"The bacteria aren't totally defenseless, however. Under those circumstances, a protein chaperone called heat shock protein Hsp33 springs to action, protecting proteins from the aggregation effect and increasing the bacteria's bleach resistance. Protein chaperones are generally defined as proteins whose function is to help other proteins."
Some things like anti biotics are misused and that's caused resistance.
But handwashing with certain microbicides doesn't create colonies of resistant bacteria on our wrists (where the microbicide is diluted) because these microbicides have a different action.
Thus, putting this polymer in all sorts of places is less likely to lead to resistance problems.
It'll also cure you though.
Effective antibacterials / antimicrobials / antitumor treatments have differential effects. Preferably harsher on what you're trying to get rid of than on you. Though the description of chemotherapy as "killing you slightly less effectively than it kills the cancer" has a lot of truth to it.