In modern society, this reaction is completely useless and utterly maladaptive. It also has a tendency to fire in people at all levels of social status, because modern society (with its dynamic, subtle, and multileveled play of social status) is confusing to the primal mind. So a depressive response can be rightly considered an illness.
Civilization expects everyone to assume the role most closely analogous to high beta/low alpha. People who have omega traits tend to be depressives; people who have too many alpha traits are sociopaths.