My environment shapes me far more than my genes. I know this because I'm not the same person who woke up this morning. Sure, my genes may predispose me to Alzheimers or Diabetes or cancer. They drive my physical characteristics, and maybe much more. But my essence is not pre-destined by my genes.

Do you really think that people can set all of their personal goals just from knowing their genome?

It's an intriguing idea that seems to be associated with Soviet-era training and the mechanization of human beings, coerced into insect-like castes, as in Brave New World, and the lovely short-story Unaccompanied Sonata http://en.wikipedia.org/wiki/Unaccompanied_Sonata (or Ender's Game itself for that matter.)

I know you don't mean coercion, but simply informed choice; but I think the rebuttal is the same: our theories are not adequate to predict such things, even if we had all the information; especially when factors like 10,000 hours of practice and motivation seem so important. At best, they can suggest a probability distribution. Or: you don't know til you try.

I guess some specifics could be useful, like a probability distribution of expected height for a baby, for his/her potential as a basketball player. However, at the very young age where genome knowledge is most effective (by revealing as yet unexpressed traits). the baby is not able to make a choice. So it would effectively be Soviet-era training.

Depression is not unique to humans. So I suspect it's a little more complex and fundamental than a failure to understand your limitations.