The MySQL startups tended to say "We love MySQL. We've gotten in the habit of taking an hour or two of downtime in the middle of the night every week to run all of our schema migrations, and we've had to build our process around that, but one we had it in place, everything's been fine."
The PostgreSQL startups said "We love PostgreSQL. We run schema migrations in real-time during the middle of our workday, and we don't have any problems."