Doing compression on the ZFS level is significantly worse than InnoDB compression.

InnoDB has a lot of really smart optimizations which make it much better than just zipping things up. Included are the modification log (so you only have to re-compress occasionally) and a dynamic scaling ability to keep compressed pages in memory rather than always decompressing. These optimizations are really only possible with an understanding of the data.

I would only consider ZFS for something like an append-only data warehouse type system.