I'm amused by the contention that running a business isn't like developing software because in business "There’s rarely a perfect decision. You’re always making trade offs. Balancing risk." That sounds like exactly what I do in software development! I guess that when I'm thinking about those things while building software I kind of have a business hat on, but it still seems an integral part of software development to me.
His underlying point about business being "soft, not hard," and the different kinds of tradeoff and risk that a CEO needs to think about, are well taken though.