If you really want to bank on Twitter going south, you can try buying puts when they're available. If you're not sure what puts are, leave this whole idea alone.
Its been a while since I've dealt with IPOs so I'm not 100% sure if that's the case anymore.
If you want to get involved, call TD Ameritrade. They can give you 100% accurate information and get you setup quickly.
http://www.investopedia.com/university/shortselling/shortsel...
If you have "funny money" that you aren't afraid to lose, there are safer and more responsible ways to experiment with the market than unprotected short positions.
You may want to read about and understand some options strategies: http://www.investopedia.com/terms/b/bearputspread.asp http://www.investopedia.com/terms/b/bearcallspread.asp
Either one of those strategies gives you the opportunity to profit a certain amount if the stock actually goes down (the width of the spread times the quantity), while limiting your exposure to just the premium you pay for the options. Your exposure is limited because you both buy and sell puts or calls for equal amounts of the underlying, so you have no net exposure to the price of the underlying.
A general word of advice about playing the market for short term gain: big guys make money off of little guys. You may win some, but usually you are doing damn well as a small time trader if you're batting above 500 at all.
If you're looking to play around with some money - basically playing a gambling game with companies - then options are a fun little game and you can manage your downside perfectly.
If the price goes up, though, you still have to buy it back. As a share's price technically has no upper limit, you could wind up in the situation where you sold a share for $10, intended to purchase it back at something like $5, but wind up having to purchase it back at $10,000,000/share because they accidentally invented an AI.
Consider the opposite scenario: you short, but the price goes up. Again, borrowing a share of stock A for $1, trading at $100. You sell that share to the market and wait for the price to fall, so you can buy and return. But, suddenly the market learns that company A is insanely profitable in a previously unknown way, and the price of the stock skyrockets. At the end of the borrowing term, you are obligated to return a share of stock A to the person you borrowed from. How much will you have to pay to get it back? This is theoretically unlimited, depending on how high the market goes. If the market goes to $200, you have lost $101 on the short. If the market goes to $200,100 (and does not fall below this before the end of the borrowing term), you have lost $200,001 on the short.
Now imagine you have borrowed a LOT of shares on high leverage (value of what you borrow exceeds what you actually have on hand to pay it back) and you can see how shorting and being wrong can wipe you out.
Good point from svachalek[https://news.ycombinator.com/item?id=6690938] below: if the borrowed stock rises high enough, eventually the lender is going to margin call you..
http://www.investopedia.com/ask/answers/05/shortmarginrequir...
[1] http://en.wikipedia.org/wiki/Options_strategies [2] www.thinkorswim.com