DoS vulnerability in #Varnish HTTP cache software.
varnish-cache.org
varnish-cache.org
Bouncing the front-end is likely to expose the backend (say, a php site) to the traffic load usually handled by varnish. This is likely to bring that (and its db, etc) down very quickly.
But the good news is that all you need to do is ship a new vcl file and there's no need to patch/rebuild varnishd binaries.