I'm sure there's no good reason why IE8 messes with this file. I'll take this random bloggers word over the thousands of smart geeks working for Microsoft any day.
Remember however,that the worst architectural decisions (coupling windows + IE?) have been taken for business purposes. Legacy and bad management can and does wipe out the benefits of legions of smart programmers.
Browser as OS, like the Crunchpad.
I mean that's why I was looking at it.