Google announces Calico, a new company that will focus on health and well-being
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This is one of those rare times that powerful people make bold choices that catalyze a shift in the world's thought paradigm. Aging will now be seen for what it is: the root of all chronic illness.
Absolutely. The goal should be to enact a vector of a new paradigm, as proactive team players synergize an out-of-the-box strategy of functionality and infotainment, re-engineering the learning curve framework of your dotted-line relationship.
This approach will surely recontextualize best-of-breed vortals, implement world-class research and innovate value-added technologies by embracing impactful infomediaries.
Imagine how much longer we'd live if we leveraged sticky e-services, brand user-centric channels, iterated seamless deliverables and matrix impactful architectures?
This will result in a significant thought paradigm shift in all things health-related, and it's a great thing that a company with as many resources and as high of a profile as Google is looking into this. Google is a company that is making self-driving cars, providing incredibly fast internet to consumers, providing Internet to suffering areas with a new idea (the Loon), exploring definitively new ideas for hardware (Google Glass) -- and now they're looking into aging.
I'd say Google guys are sufficiently more respectable than the political chameleon who's lobbying DC today [1], and just recently directed considerable resources on ads advocating a host of anti-environmental causes [2].
[1]: http://www.politico.com/story/2013/09/mark-zuckerberg-dc-969...
[2]: http://thinkprogress.org/immigration/2013/04/26/1925921/mark...
A lit class isn't going to make any comment on a phrase like that, or management speak in general. Management speak is just a jargon.
But your comments are factually wrong. None of Google's products you mention are new or really that much better (so far.)
>> Google is a company that is making self-driving cars
So is every major car manufacturer out there. Who's ahead of the game? I don't know because Google gets all the press and fawning from fanboys--like you.
">>providing incredibly fast internet to consumers
Experimenting in a few ares with plenty of subsidies doesn't count. The much hated Verizon has done a LOT more on that regard http://en.wikipedia.org/wiki/Verizon_FiOS
">> providing Internet to suffering area with a patently new idea (the Loon)"
Not providing anything yet, just experiments and Loon is not a new idea at all. http://online.wsj.com/public/article/SB120347353988378955.ht...
">> exploring definitively new ideas for hardware (Google Glass)" Not a new idea at all. Different thinking of course but the verdict is still out.
One day--the focused like a laser--Google will manufacture their toilet paper and you'll be here to wonder how we managed without toilet paper before Google invented it.
It's Google. They have the right people, the right ideas, the resources, and they started first. Source: I'm a prof in a related field with graduated PhD students at Google.
The Google cars get press because they are really very good.
http://ideas.time.com/2013/09/18/finally-the-war-on-aging-ha...
This announcement could be interpreted as strong support for the general concepts that Aubrey talks about.
> So soul-destroying has this knowledge been, for almost everyone, that we have constructed our entire society and world view around ways to put it out of our minds'.
Absolutely ridiculous. Besides the fact that I think a 'soul' is a poorly-defined construct and thus hard to crush, I really don't see a problem with death; to me it's just as necessary as birth. Sure, it's sad when someone dies, and death can be a traumatic experience, but it's also simply part of being a biological organism. I suppose I find some agreement with de Grey in that large portions of societies fear death and try not to think about it. However, perpetual avoidance through the declaration of war on Death seems practically infantile in view.
You know, as opposed to not tiling the universe in anything.
This tends to be glossed over in discussions of his work, but Aubrey de Grey is specifically interested in reducing the (currently inevitable) human suffering associated with aging. Clinical immortality would be an eventual side-effect of succeeding in that mission.
Every manner of treatable and correctable disease and condition is "part of being a biological organism," but it seems absurd to hold such a standpoint if you're not also in favour of discarding modern medicine in order to die slowly and painfully from cancer.
laugh.
Absolutely everything we have built with technology is not simply part of being a biological organism. Who are you to say what being a biological organism is about? For that matter, what's special about biology (nothing, but that's a different discussion)?
Smallpox is simply a part of being a biological organism. Fighting with other organisms to the death is part of being a biological organism. Survival of the fittest is part of being a biological organism. But we're better than that. See, we have pretty powerful brains that allow us to escape the endless cycle of suffering and death that is "being a biological organism". You're not forced to use yours for that purpose, but don't act like there is some bright line between all the other supposed rules we break and curing death. It is all part of the same progression.
Ah, I see, you're engaged in a 'War on Metaphor'.
Let's just go ahead and pump the brakes here before we start clapping each other on the back and talking about shifted paradigms. I'll gladly join in the happy-clappy fest once some actual results come through. But saying we've catalyzed a shift in the world's thought paradigm (that is a really pretentious way of saying "this might make people think differently", by the way) at the announcement of a new product might be just a wee bit premature.
This is thought provoking - if even a perfect solution to such a problem won't give us what we want, then we do need to "make people think differently" and try to focus on a different, bigger problem than the current approach of trying to strike out separate illnesses.
By the way, allowing medicine to think about not only "how to bring a broken-person to average" but "how to bring an average person to above-average" would also require a major change in the way of thinking for the whole area. Some homo sapiens are extremely resistant for diseases, some are smarter than average, some have much lower aging damage. Instead of thinking how to fix a genetic disease by replacing a broken gene with the "average" one; we should think about what is the best that we, as a species, could be.
having a massive stroke/heart attack/aneurisma? at least you pop and you're gone. going through chemo/radio for months/years to slowly, painfully wither away is bullshit.
same is true for all those diseases, parkinsons, alzheimers, etc.
fuck them all. they are the bane of our existance, literally. pure evil.
Its not instant death, but the process of a slow death that is the enemy.
3 years increase from a non-infant mortality related improvement is actually pretty huge. I'd have to look it up, but I think the impact of non-infant vaccinations would be roughly a similar sized increase.
Going from 80 to 83 (for example) is nice, but it doesn't have a radical impact on how we should live our lives - going from 80 to 160 could do that. If we want major improvements, then we either need to make sure that the other things are cumulative (say, that we can get 20 disease-cures to add 3 years each); or we need to look in completely different directions.
It depends on what you see as a goal - in the long run, I believe that we can get to lifespans measured in centuries, because it's technically possible as seen from other lifeforms. If the marginal improvements due to curing diseases can't get us there, then we should investigate other options how to achieve that, instead of treating a 5% increase as "pretty huge" and being satisfied with that.
Take a look at, for example, http://youtu.be/qMAwnA5WvLc (TEDx, Aubrey de Grey) linked in another thread.
All we're doing today is announcing a moon shot.
We need to get out of that hole first. Google is doing the right thing.
But seriously, the fact that the first thing they do is start a corporation to control the science is not exactly comforting to me. Genentech is known for selling Avastin, their drug that fights cancer for $55k after they received harsh criticism for the proposed cost of $100k+/year.
http://en.wikipedia.org/wiki/Bevacizumab#Costs
I fear a future where "all men are created equal", but only some can afford to become immortal and others cannot. We already see some of that now. Tons of ethical questions around this topic.
It is a moral imperative to make sure that short-sighted class warfare does not cut off the nose to spite the face by destroying this work under the guise of egalitarianism, because we can not turn on a dime and immediately grant it to everyone on day one. Yes, the rich will get it first. We need to ensure that market mechanisms remain functional and that they end up subsidizing the research the rest of us need. If we build gates and walls, they'll just end up captured in a heartbeat. Don't let them be built.
(Once the market has chewed on it and made it as cheap as possible, consider subsidizing it or something, but for the love of Life itself, don't break the market and destroy the research before it even happens. Seemingly suboptimal situations may need to be relatively briefly tolerated to make sure this happens at all.)
There's a difference between making your money back to cover the cost of research and development while making a profit, and plain old greed. A 20 year lifetime on a patent with a 3-7 year window of exclusivity means you might be dead before you can afford treatment. That's one of the ethical issues that we will hopefully address in a sane and logical way as we move forward. How much money should one be able to make if they are adding days to your life?
I do agree that this type of thing may be helpful to humanity. I just cast a skeptical eye knowing how the drug industry has worked in the past.
(To which the natural next slur is "Oh, you want no regulation then?" No, I strongly believe a free market requires some basic maintenance to harness properly, and I'm a particular fan of internalizing externalities via government action. However, virtually by definition, if patents are being "abused", that is not maintenance; that's sand in the gears.)
I consider the idea that we live in some sort of anarchic free market wonderland today to be nothing more than propaganda, used by those who want to use government to take even more control over your life. There's very few free segments of the modern market that are even remotely free; they simply aren't as centrally managed and regulated as they could be.
Free market capitalism isn't fair. All the dynamics and mechanics of capitalism have nothing to do with fairness.
Imagine having to live in a world where all the positions of power are permanently occupied by people from the generation of your great-grandparents.
The base state of the world that we live in is that everybody dies. Your hypotheticals about how horrible it might be to live in a world where people might not die have to be pretty horrible to compete with what is already true.
(Mind you, this is not an unleapable bar, in my opinion, but it's much higher than you just leapt.)
We can stack them like cordwood for a while, but that gets messy, inconvenient and after a while, a bit smelly.
Generations eventually dying off keeps the human race moving forward in many ways.
You propose that the best solution to this is kill everyone over 80.
That would make you a psychopath.
Your comment is the epitome of ageism.
Yes, the rich will get it first. But then think about what will happen: they will start living longer, and as a result, accumulate even more wealth over their lifetimes. While the poor will have 30-35 years of productive work-life, the rich will have much longer. Combined with the already large difference in their earning power, this will lead to a world where the rich not only life much higher quality lives, but also longer lives.
Don't cut off your nose to spite your face.
I would rather no one have it than institute a system of even more perpetual control. We have already signed most of our existence over to the rich and the only equalization is that they die, too. It isn't cutting my nose off to spite my face to not want to live 70-80 years under the continually-strengthening ownership of those who will live to 200. (And, similarly, me living to 200 so I can work all those years for those who'll live 400 doesn't strike me as particularly awesome either.)
Universal health care is a thing, outside America.
Your argument hinges on a hoary anti-Marxist critique. As one example alternative approach, the hundreds of billions, if not trillions, of dollars handed out to financial institutions and/or forgiven in legal penalties could have been used to reimburse companies for creating successful health technologies and treatments. It's a matter of policies and priorities, some of which are broken and some that aren't (Sturgeon's Law), and the market structures of medicine operate in the way that it does for specific reasons not necessarily aligned with benefits for those who are dying or sick.
tl;dr: TIMTOWTDI
I was born in a world where two things in life got to everyone: death, and taxes. They've already "relieved" the elite of taxes, and now they're looking to do the same for death.
No. We are not their cattle, and they are not our shepherds.
You want immortality, robots, and post-scarcity awesomeness? Great. Make it for everyone.
Don't develop The Future just so the capitalist elite can exploit even harder.
And you say they're the ones serving Life?
On the labour/production side a technology seems to be creating wider income gaps. For the winners it is a lever with which to create more wealth. For others, they are competing with machines and poor countries (enabled by technology to work with rich ones) for work.
On the product consumption side, the gap is pretty small. The cheap netbook that almost anyone in Europe or the US can afford is not much different (in price or performance) from the one used by a billionaire. No matter how rich you are, you can't get a better smartphone than the models you can see in any bus. Even the low end (50-$100) smartphones are getting decent. I expect smartphones to be as ubiquitous as dumb ones soon, that means the gap between rich British & bangladeshi (measured in smartphone wealth) is plummeting.
Who knows what future waves of technology will look like, especially medical technology.
I think the appropriate response is keep an open mind and see where stuff takes us. Don't bind your thinking to past paradigms. Go read the Communist Manifesto. Realize how it is a product of its time, the industrial revolution. It takes a lot of contortion to try understanding the world by that paradigm. For Adam Smith, technological efficiency was about making pins.
I always feel modern medicine should focus on raising life quality for as long as we are alive, rather than extending life itself. But of course this view is painted by the large number of old people living in inhuman conditions we currently have.
I hope for more youth, not just more life.
Also slowing down growth is much more palatable on a basic level if you have that much more time to enjoy what you have and get what you don't have yet.
Accelerate existence by whatever means necessary; availability will follow.
You assume that those in power will want to make more like them and I think that is mostly unlikely. Nothing attracts the powerful like an insurmountable advantage. Being able to outwait your potential competition at that scale is powerful and I have a hard time seeing powerful people wanting to make their potential competitors as powerful.
If you think we'll get to a point where nobody can disrupt the anti-aging industry ever, and nobody will be able to make it cheaper, well, you're pretty pessimistic. Because the one constant we seem to see is (immortal) corporations being disrupted by little startups. Corporations right now live forever and yet they don't stay in power forever. The same will go with this.
I don't see why you'd say this. Economic mobility in the developed world is steadily shrinking. I don't see that shrink getting better if the rich can play on the time scale of centuries. Or if the corporations they own can do so.
As has been noted numerous times, poverty means you have to think "tomorrow" rather than "a month from now" or "a year from now". When you can think "eight decades from now" or even "two centuries from now", you are in an incredibly powerful position and I am extremely skeptical that people with that advantage will give it up for the rest of us.
Of course, universal access is far better, and we should keep that in mind, but if it takes profit-motivated corporations to bring the technology into existence in the first place, then so be it.
Giving the rich the tools to exploit the rest of us even further seems pretty foolish. Likely, even inevitable--but no less foolish.
Therefore, if you stipulated that such an invention could only happen if it started off in the hands of the powerful, I would still take that bargain.
This is not demonstrated at all. Increasing existence and production of food hasn't tackled food insecurity and hunger, for example. That something exists, even if cheaply, does not mean it will become accessible.
Um... what about the millions of lives saved by the green revolution and agricultural advances? Hunger hasn't been eliminated, but technology has increased the carrying capacity of the earth by a few billion.
Re. technological availability: see the falling price of mobile phones, personal computers, Internet connections.
That future is now. We already have first-world countries with medical technology that allows its citizens to live an average lifespan much longer than those in countries where such tech is unavailable. Not to mention the everyday technologies that indirectly extend "effective" lifespan -- every hour not spent gathering cooking fuel, preparing food, washing clothes, etc. is an hour you can spend "living". Even in said first-world countries, there is a dichotomy: those who are rich & influential enough to take advantage of expensive & cutting-edge medical treatment, and those who are not.
Actual life extension therapies are just the above, writ large. I don't see any difference between this tech and any other "early adopter" tech, which is always expensive and limited in availability. We can only hope that such technology will become cheaper & more widespread and trickle down to the rest of us in time for us to make use of it.
How else would they do it?
This is not about making the world a better place. This about allowing the elite that can afford it to live forever.
Imagine you have two groups of people: Group A and Group B. You are voting on a technology that can prevent 90% of deaths in Group A. Do you vote yes or no?
If you vote no, congratulations, you just condemned a large group of people to continue dying for the sake of egalitarianism.
(The reason this thought experiment is powerful is that it strips the scenario of value-judgments such as "elite" and "poor.")
Imagine you have two groups of people: Group A and Group B. Group A is living longer but unhealthy and Group B is living shorter but extremely healthy , which one do you pick - I rather pick Group B ... dont know whether Calico will be about living longer or living healthier - its not a easy thing to crack but I hope they succeed ...
Oh, I'm sorry, you don't consider yourself part of the elite?
61% lack Internet access [1]
35% lack basic sanitation (e.g., toilets) [4]
26% don't have plumbing (e.g., water they can get from pipes in their house or yard) [2]
23% don't have electricity [2]
14% lack access to clean water [2]
14% lack access to health care [2]
13% suffer from chronic undernourishment [5]
11% can't read [3]
14% is about one billion people. Maybe you look at that and think, hey, 86%, doing pretty good! But if this many people can't even get access to even the most basic of technologies today, what makes you think most people, even people in the developed world, will have access to whatever mythical mortality-defying technology people are speculating about here? It's all such speculation as to what they are doing, the question is practically not worth answering. But if extreme life-lengthening technologies are truly on the table, the potential for an Elysium-like scenario should be taken seriously.
(Also, point of clarification: what do you mean by "intrinsic reason"? Can you give an example of an intrinsic reason something would be limited to the elite?)
[1] http://en.wikipedia.org/wiki/Global_Internet_usage
[2] http://www.globalissues.org/article/26/poverty-facts-and-sta...
[3] http://www.statisticbrain.com/number-of-american-adults-who-...
[4] http://www.unwater.org/statistics_san.html
[5] http://www.worldhunger.org/articles/Learn/world%20hunger%20f...
Bill Gates is saving thousands of lives by trying to wipe out diseases that generally affect poor people for very little money per life saved. While in the US millions is spent per person to provide longer lives for a few people.
What? The average life expectancy in the US is 79 years old... http://en.wikipedia.org/wiki/List_of_countries_by_life_expec...
Life expectancy is nearly 80 years in the US at this point, even with the explosion of cancer, heart disease and diabetes that has come with obesity in the last 30 years.
You'd have to be defining old age as 140 for your statement to make sense.
1 - http://who.int/mediacentre/factsheets/fs310/en/ 2 - http://www.who.int/cardiovascular_diseases/publications/glob... There are tons of statistics at http://apps.who.int/gho/data/node.main.CODWORLD?lang=en for the full picture.
I guess this fixes that.
We had various interactions with both the Google Health and Microsoft HealthVault teams. They were both making patient facing apps, ours was physician (and staff) facing.
We had a patient facing app, because all the hospitals thought it'd drive admissions.
But at the time no doctor would trust patient's data.
To the best of my knowledge, that hasn't changed (five years on).
The "quantified self" movement may change the perception of patient gathered data. When data collection is automatic, standardized. More importantly, when doctors are doing it for themselves, so are familiar with the tools and culture.
So, in short, Google Health and MS HealthVault were just wishful thinking. There was no "there" there.
You're probably right. But any advantages in medicine eventually will boost available level of tools to all. Well it worked as this so far. Elite is just able to get the best much earlier - but that doesn't mean we should stop all scientific progress and reset to the level of medicine everybody can get.
That is how all products first become available. The rich fund the R&D and scaling.
We'd all still be living in primitive civilizations if your approach ruled the day.
I'd love to see Google work on initiatives to give the world's poor access to clean water and basic healthcare. Those are awesome causes -- maybe the world's most awesome. But if we categorize pressing third-world health issues as the World's Most Awesome Cause, well, aren't age-related diseases the World's Second Most Awesome Cause?
We should for sure allocate more resources to the World's Most Awesome Cause. But why are people attacking funding for the World's Second Most Awesome Cause? Convince people not to buy top-tier smartphones, or expensive cars, or big houses, and donate to charity instead. But don't try to convince people to die of heart disease. Even if this new Google initiative isn't the absolutely most optimal way to spend money to serve humanity, it's pretty high up on the list.
Please remember that about two-thirds of all deaths world-wide are caused by aging [1]. It isn't just the elite who are getting heart attacks, and long-term, I'd be shocked if it were only the elite who were receiving effective treatments to prevent them.
1 - http://en.wikipedia.org/wiki/List_of_causes_of_death_by_rate
Edit: formatting.
Not to mention, it's a more attainable goal. It doesn't help much to keep the body going for 50 more years if you can't also keep the brain going. I believe these are very different problems. If you can somehow solve both, it doesn't help if you can't feed and house all these people.
Aubrey de Grey believes they are not different.
If he's right, the only way you could keep people perfectly healthy up to age 80 without them living much longer would be to execute on his plan (or a similar one), and then kill people once they got old enough.
Google believes in capitalism. They will offer goods and services to people who can afford them, and they will also work to make their products more accessible to those with limited resources.
I personally believe Android will have enormous long-lasting positive impacts on the rest of the world. A $25 smartphone ... A $10 smartphone... A $5 smartphone... Giving access to instant communication, and huge amounts of information, will in the long run dramatically improve human lives. My personal opinion.
The only pure capitalist societies are anarchist hellholes. Among nice societies, capitalism is implemented all sorts of different ways with the things capitalism does poorly[1] papered over in different ways.
[1] law enforcement, basic standard of living for all, various economic regulations to address market failures, e.g. I can't legally plug in a transmitter at 100MHz and 1000 watts and black out WNBC in my neighborhood, and can't sell capitalist let-the-market-decide food out of a roach den
gdulli was criticizing a corporation for providing goods and services that a relative minority of the wealthy can provide.
I assert that that criticism is only valid, if you have fundamental problems with capitalism itself. The way I stated that was, "you either believe in capitalism, or you don't." I am not aware of a better way to state that. It's a matter of faith / belief / an assumption. If you share in that view, you can correctly engage in one set of logical discussion. If you do not share in that view, you can only engage in another set of logical discussions. Watching someone criticize a corporation for providing luxury goods is ample evidence that they're having the wrong kind of discussion. Their first necessary step would be to convince me that we should abandon capitalism. Period. There's no other first move in that game.
I hope what you really meant was far, far better than what you made it to sound like.
They aren't mutually exclusive goals; working on the social/political/distributional problems that prevent most people from having a high quality of life is not exclusive with working on the health technology problems that mean that no one is living 150+ years.
And I'd rather see a high quality of life for everyone on Earth for 150+ year life spans than either of your options.
Silliest thing I've read all day. There are huge costs associated with extracting resources here on earth, let alone from the stars. And even if "the universe" is infinite, no new matter is being generated.
> Tim Cook, Chief Executive Officer of Apple, said: “For too many of our friends and family, life has been cut short or the quality of their life is too often lacking. Art is one of the crazy ones who thinks it doesn’t have to be this way. There is no one better suited to lead this mission and I am excited to see the results.”
They might have different opinions or frustration with the competition, but most of what they focus on is not letting the company die from the inside. i.e: AOL/Palm/HP/Netscape couldn't innovate and imploded.
Eric Schmidt was on Apple's board up until the day shareholders (implicitly) deemed it to be a conflict of interest. I'm sure he was a great asset for Apple learning the importance of internet services. It's a shame that short-sighted investors are too captivated by competition to realize how cooperative Silicon Valley really is. There are only a handful of situations in tech where crushing your competition is actually a positive strategic move.
The rising tide floats all boats.
Sponsored by Sergey Brin and Mark Zuckerberg (and Yuri Milner).
Instead, all the future-advancing progress seems to be made by independently rich individuals; and also not by the "aristocratic-rich" families, but by noveau riche upstarts such as Brin, Musk and others. What does it say about our current, traditional institutions if they seem unable to do that? Are they broken, and can they be fixed somehow?
"What I care about is that Google has become a machine that turns advertising dollars into fundamentally groundbreaking new projects like Google Glass, Project Loon, and self-driving cars. They’re not just trying to make money: they’re trying to use that money on far-fetched moon-shot projects with the chance to be genuinely revolutionary. I admire that."
Now they are investing in a new realm where they are "excited about tackling aging and illness." Google's ambition, and vision is inspiring! Hopefully we see some innovation in this sector from this investment.
What does that refer to?
[1] http://business.time.com/2013/09/18/google-extend-human-life...
Although perhaps Larry Page just wants to avoid the strange vagaries of non-profit governance, if I were to guess why.
Regardless of motivation, I'm happy to see investment in this domain.
Steve Jobs, for example, had billions of dollars, had his genome sequenced, and probably tried very hard not to die so young. I bet if he had known 10 years earlier that he was going to die from pancreatic cancer, some of that money would have gone into searching for a cure.
Larry Page might live a perfectly healthy life, die in his sleep at 101, out living most of us. However, if you've got that kind of money and influence, why not buy some real insurance.
Steve Jobs is actually a terrible example. To quote wikipedia, "Despite his diagnosis, Jobs resisted his doctors' recommendations for medical intervention for nine months,[170] instead consuming a psuedo-medicine diet in an attempt to thwart the disease." Pseudo is Greek for "false." And if you want cancer solved by the time you get it, you probably have to pony up the money before your diagnosis.
I'm not disagreeing that medical advances are relatively slow, but on the scale of human life, Page has probably at least another 40 years of advances left to see. And that's a lot.
9 months is not much time. If Steve were just an average person, his condition probably wouldn't have been discovered as early as it was. He simply squandered the little extra time that he had. There's no guarantee that he it wouldn't have killed him in the long run even if he had gone under the knife earlier. Pancreatic cancer, in general, is pretty deadly: http://www.cancer.org/cancer/pancreaticcancer/detailedguide/...
Randy Pausch had pancreatic cancer and died at 47: http://en.wikipedia.org/wiki/Randy_Pausch
Sure, it's great that we can predict with a higher accuracy what diseases we might get. Now it would probably be helpful if we could cure most of them.
It would be really interesting if we began noticing a medical analogue to Moore's Law in the next few decades (though I don't know how you'd measure it). Supposing conservatively that medicine is 100x better in 2013 than in 1900, one might expect medical knowledge to double between now and 2030. The size of the advances in computing from 1900-40 and 1940-80 differ by several orders of magnitude.
Of course I don't think we have the data to assign a model right now so this might be BS.
The capital us youngins have is time and ability if not money. This is a great example of moguls and companies willing to put that resource in given an availability of the talent and ability.
I was thinking on taking some graduate program that would help the transition in this kind of companies; does anybody knows a university/program that would help? I have checked some graduate bioinformatics, but I am not sure what would be more helpful in the long term.
Any idea/suggestion?
In many areas and locals, not necessarily Silicon Valley, a pure engineering man is seen as a lackey. An engineer with business cred is considered valuable, just my experience.
My intent is to have a technical role in the space, not a management one. I can imagine how most of the problems facing require machine learning and statistics, so I am more interested on how to complement these skills to be able to transition into an space that fascinates me.
You can learn what you want on the technical side outside of college. Now, if you want to be in a research institution or academia, you don't need the MBA, but then there is the whole can of worms of how to gain influence enough to do the research you want.
> So I’m tremendously excited about the innovative new way we’re funding this project
Are they doing something other than just dumping money into it, siphoned from their core business? Or am I reading this wrong?
This is the greatest news I've heard in a long time and even if it ends up in nothing the attitude alone is commendable.
This makes me wonder just how much Google works with the US government. I'm not saying the result of whatever Calico wants or will do (because it's all pretty vague right now) is a negative.
But Calico seems to come at a time when Obama is pushing for universal health care, which will be a huge industry. Last I heard, it was estimated at $1.1 trillion.
It just feels like the US has a tendency to take something good (universal health care), and make it into something bad ("We will use this to profile/monitor every US citizen").
The US already has HIPAA, so I don't get the point. This just seems like a weak attempt to say something negative about Google's announcement.
If this weren't the case, some Americans wouldn't have a problem with 'divulging' their medical history.
Health care is based on science, you're right, but there are factors that influence what is researched and where funds go. Plus, putting it in practice or implementing it according to the right policy; this is another issue.[1]
Also, I think you're undermining the magnitude of lobbying.
But Google is a huge company, with a lot of power and capital. So, like I said in response to someone else, I am very interested in the details of Calico.
[1] http://billmoyers.com/2013/05/18/blinding-us-from-science/
And where is Google advocating for cuts in public science spending, or lobbying to get regulations reduced on harm-causing environmental agents? This is a non-sequitur with respect to Calico.
Part of big data is transparency, removing ignorance. We overspend on healthcare and treatments that don't work, precisely because we haven't crunched the numbers and informed the public and based policies based those insights. Obamacare took a lot a flack over this ("death panels!!"), but if you want to talk about optimizing health, then using computer science to evaluate medical data to target spending at stuff that works and extends life and well-being the most is a huge win.
Standing in the way of that is conspiracy nuts who obsess over the privacy of their vital fluids and that somehow, scientists recommending that your favorite treatment is nothing more than a very expensive placebo is a death panel.
In a perfect world, no one could be denied healthcare, and everyone's medical records (anonymized) and history would be open to all scientists in the world for exploring the connections between disease.
I'd certainly like to know that 10,000 other people, who have the same gene X as me, who also developed symptom Y after behavior Z, and that scientists could also make that connection and begin to figure out how to target treatments, rather than counting on some hope that some study will get the right participants with the right set of histories to figure this out.
Seriously though, I wouldn't trust any company connected with Google for 'health and well being'. Their total disregard for privacy would imply they are not working in my best interest for health either.
To the contrary, they have utter regard for your privacy. They advocate for governments to have more respect for your privacy, as well.
Alfred knows everything about Bruce Wayne. Google is Alfred, except he doesn't even take a salary - he wants to show you advertising that you would think is high quality, and he promises to never sell your personal information to the advertisers. Pretty damned good deal, if you ask me.
There is literally no evidence anyone could provide you, that would make you change your opinion.
And I can't claim that I'm much different, if I'm honest, unless Google execs admit to it. Or unless journalists discover examples of prosecutors admitting evidence in some court, to convict someone, based on data that could only have been acquired with Google being complicit.
You seem to forget that Google pulled out of China, rather than comply. How much money did they leave on the table, there?
It's not Google's fault you only started looking for the information after Snowden's stuff.
You should calm down a bit and try to adopt more reasonable stances if you actually hope to make a difference.
As to that specific question, I bet it's because Google's Privacy Policy says:
> We will share personal information with companies, organizations or individuals outside of Google if we have a good-faith belief that access, use, preservation or disclosure of the information is reasonably necessary to:
> meet any applicable law, regulation, legal process or enforceable governmental request.
Lavabit's policy[1] said:
> [...] we will not surrender any private information without a court order; [...].
... so I guess they kind of indicated that they could be convinced to share private information, although they didn't do it in the form of a positive assertion like Google.
1. http://web.archive.org/web/20130805154359/http://lavabit.com...
Hey, remember this?
> Should be titled the Banality of Google Strawmen for the often repeated conspiracy theories of Google working with the NSA.
> There's simply no way Googlers would tolerate something like secretly sending user data to the NSA, it would be too hard to prevent internal employees from revolting.
> As an employee, I'd rather Google lose money and stock price and have the government shut them down, than send a firehose feed to the NSA.
https://news.ycombinator.com/item?id=5807106
Well, did you lose your Google job yet?
If the NSA is getting any kind of dragnet data, most likely it is via external network taps, intercepting non-encrypted SMTP traffic, or non-encrypted intra-datacenter fiber traffic the same way they tapped 'dark fiber' undersea cables of the Soviet Union during Venona.
Google cares very much for user privacy, it is part of the corporate culture.
Try again.
It could take 20-30 years for their research and development to catch on, but I'd imagine some of Google's biggest followers/clients are in their 20's, 30's, 40's.
They wouldn't have launched this company if there was no "end-game" or no ultimate goal, and retaining customers indefinitely seems like the ultimate goal for any company.
Like, there are feel-good stories like Dean Kamen's Slingshot (IIRC, he partnered with Coca-Cola to distribute the things) but I have absolutely no idea how well such things work in the field and the papers written about things like the Roundabout PlayPump are pretty damning.
Cool.
http://www.amazon.com/Great-Mambo-Chicken-Transhuman-Conditi...
I hate to be this guy, but...
> OK so you’re probably thinking wow! That’s a lot different from what Google does today.
Not really. Google is in a business of selling ads. In addition, they do make money on selling/sharing/exchanging information, mostly indirectly.
> But as we explained in our first letter to shareholders, there’s tremendous potential for technology more generally to improve people’s lives.
.. and shareholders did not care about that. If you own shares of a hospital chain then you may care. But when you hold shares of Subway, Coca-Cola or Google, in those particular markets you care less about people's lives. You care about bottom line.
> So don’t be surprised if we invest in projects that seem strange or speculative compared with our existing Internet businesses.
We are not surprised. But since you sun-setting pretty good, useful projects like Google Reader, and you taking Jobs advice of "stay focus on only couple [most profitable] projects at the time", we ask: "where is the catch and how you gonna make money _otherwise_ than selling info or exchanging it?"
Just recently I have cancelled my 23andme kit (they gave me some hardtime though and never fully recovered the fee (taking legal action is simply not worth the $)), because after doing some research I found it that 23&me owner is family with Brin. There is no chance in this world you will tell me Google will not try to make money off of my DNA this or another way)
Obligatory and irrelevant Google Reader reference. Check. Right, the world would be better off if Google spent more time investing in yet more social sharing web app features, and not on reducing high way fatalities or increasing health.
Missing. No mention of PRISM.
None of my friends are homo economicus, even qua investors. As much as we love earning more money, we also care about other people. We also like when the companies we part-own aren't evil.
As for the fact that 23andme's founder and Brin are married...you do understand the marriage of two CEOs does not equal the merger of companies...especially when the CEOs don't own the companies.
(Yes, some problems might come in if they invent something that can keep you young if you start at 30, but doesn't do anything if you start at 65, however the long term benefit would still be amazing and maybe make the Republicans' dream of getting rid of Medicare finally come true...)
To the people who say death is natural: Many, many natural things are bad (high child mortality, smallpox, etc.) and many artificial things are good (antibiotics, vaccines, the computer letting you read this comment.) Naturalistic Fallacy.
To the people who say death is good: No it's not. My parents had me when they were older. Now my dad has a kind of cancer that is associated with aging (multiple myeloma.) He was diagnosed my first year of college (luckily he has been doing rather well considering for five years now.) I get to look forward to loosing him before I turn 30. I don't care why you think death is great because of its benefit to society; I don't want to loose my dad. Also, my kids will almost certainly never know their grandfather, just like I never knew mine (He died of the same kind of cancer a few months before I was born,) which is sad. You are severely underestimating the value of not having to watch people you care about shrivel up before your eyes and be irrevocably destroyed, knowing that there is nothing you can do to stop it.
The top comment makes me feel like I'm missing a magical paragraph in the OP that details their cure for death, ugliness and stupidity.
Presumably, its going to do research (probably secondary with an aim to commercialization, rather than basic research) on health problems, particularly on aging and aging-related diseases.
> The top comment makes me feel like I'm missing a magical paragraph in the OP that details their cure for death, ugliness and stupidity.
Its not a startup looking for venture capital that needs to demonstrate an MVP to attract investors in the near term, its a project that's already funded by Google as a small (by comparison to Google's available resources), effort. Efforts like that don't need to have a product on day one, they need a mission.
The fact they open Calic makes me hate them. They could have gone in every sector, but not in the one that is there to actually improve our life. They will algorithmically help kill much more people efficiently. Money powers the healthchare system.
This post could not be found. Your URL may be incorrect, the post may have been deleted, or this account may not have access to the post.
This is the URL it takes me to: https://plus.google.com/+LarryPage/posts/Lh8SKC6sED1
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I’m excited to announce Calico, a new company that will focus on health and well-being, in particular the challenge of aging and associated diseases. Art Levinson, Chairman and former CEO of Genentech and Chairman of Apple, will be Chief Executive Officer.
OK … so you’re probably thinking wow! That’s a lot different from what Google does today. And you’re right. But as we explained in our first letter to shareholders, there’s tremendous potential for technology more generally to improve people’s lives. So don’t be surprised if we invest in projects that seem strange or speculative compared with our existing Internet businesses. And please remember that new investments like this are very small by comparison to our core business.
Art and I are excited about tackling aging and illness. These issues affect us all—from the decreased mobility and mental agility that comes with age, to life-threatening diseases that exact a terrible physical and emotional toll on individuals and families. And while this is clearly a longer-term bet, we believe we can make good progress within reasonable timescales with the right goals and the right people.
Our press release has a few more details though it’s still very early days so there’s not much more to share yet. Of course when Art has something more substantial to communicate (and that will likely take time), he’ll provide an update. Finally, thanks to Bill Maris for helping bring this idea to life and getting Art involved, and to Sergey Brin for consistently supporting 10X thinking like this. It’s hard for many companies to make long term investments. So I’m tremendously excited about the innovative new way we’re funding this project. Now for the hard work!
http://googlepress.blogspot.com/2013/09/calico-announcement....
http://www.theguardian.com/society/2013/jun/13/antibiotics-c...
I think it will be much more of a problem in the long term than aging (pun not intended).
Replaced by bunch of Youtube links and wikipedia.
Google is getting into conflict-of-interest endeavors.
Calico.com is registered to Oracle and there's nothing there.
(Question is only half-serious)
stop getting emotionally attached to google products. they aren't your children.
They already went thru one iteration of electronic medical record, which is too bad because it sounded interesting but the first time I heard about it was on a READER feed as it was being shutdown. Before READER shut down of course.
Isn't that fascinating ?
Its more like Genentech (at least in focal domain) than Monsanto, but "Genentech for Nerds" would be still just be Genentech -- who, incidentally, shares its Chairman with Calico.
If we had a regime where anyone could voluntarily place any therapy into their own body, we'd move a lot faster. Yes, a few more people would die in testing. But a lot more lives would be saved by the therapies produced.
One of my biggest clients is in the medical device industry. From the surface appearance, any company could make a simulacrum of their main products with perhaps 90% cost-cutting... but life-saving devices are not like inferior iPods or graphic designs. It's not just things like a crappy user interface, poorer display quality and periodic crashes interrupting your musical flow you would have to deal with if any New Jack could make medical devices, but infection, worsened health, extraneous visits to doctors, untraceable health conditions, lack of accountability by your doctor and yes, death through everyday use, etc. After hearing conservative cheapskates bitch about wasted expenses of FDA regulation and liberals bitch about "how easy it is to walk around the FDA," I have come to fully doubt both (read: realize how much they're talking out of their ani) and respect the FDA after working in such close vicinity to them.
And anyway, yes anyone can voluntarily place any therapy in your body- you just can't get a corporation to help you with it in the U.S.
In the age of patent medicines where you could freely use any kind of "medicine" or treatment this was not true at all. Medicine is not simple to understand or develop and asking the average person to make this evaluation is enabling a system that will take money from people in exchange for making their health worse. The kickstarter model is not appropriate for medicine.
But yeah, Google has managed to suck the oxygen out of others with every new announcement (self-driving cars are one example http://en.wikipedia.org/wiki/Autonomous_car#History )
BTW: Calico... what a non-ValleyHipster name...
Yeah... they should have gone with Doctr.