I see no reason why the IDE couldn't do that with multimethods. The trigger might have to be a little different but otherwise I see no issues here.
The "dot-autocompletion" has a pretty good usability in my opinion. You write down the name of the variable, enter a dot and you get a filtered list of methods that "make sense" to call on the receiver (key word: discoverability of the API).
How exactly would one implement the trigger with multimethods? I think this is an important consideration to make from a usability standpoint.
I admit it's a little weird, but not so weird people couldn't get used to it.
x y x DoSomething
However, I don't think I've seen an IDE for PostScript or Forth