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Comment by GotAnyMegadeth | Hacker News Reader

Kind of on topic: I was surprised to find out that Nicotine is thought to be more addictive that Heroine...

http://en.wikipedia.org/wiki/Nicotine#Dependence_and_withdra...

Nicotine itself (without the byproducts that happen when burning tobacco) is not even that bad [1] (deadly in relatively low amounts but unless you take it concentrated it's very hard to reach those levels). Unhealthy? Yes, but probably not much worse than caffeine [2].

Besides, Nicotine itself is not that addictive "Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties. However, after coadministration with an MAOI, such as those found in tobacco, nicotine produces significant behavioral sensitization, a measure of addiction potential." [3]

[1]: There are a few studies that look at nicotine excluding cigarettes on Google Scholar.

[2]: Compare http://en.wikipedia.org/wiki/Nicotine#Pharmacology and http://www.energyfiend.com/harmful-effects-of-caffeine

[3]: http://en.wikipedia.org/wiki/Nicotine#Psychoactive_effects

>>[2]: Compare http://en.wikipedia.org/wiki/Nicotine#Pharmacology and http://www.energyfiend.com/harmful-effects-of-caffeine

Cough, was that completely honest? since you linked to Wikipedia for Nicotine, I suspect you did know you'd get lots of really good effects by linking to Wikipedia for caffeine. :-)

http://en.wikipedia.org/wiki/Health_effects_of_coffee#All-ca...

Wikipedia had a lack of harmful effects of caffeine (or at least none written in a way I as a layman can understand) and I thought a site with articles about caffeine selling caffeine products would make an okayish substitution.

Again for nicotine there is no convenient list on Wikipedia, so:

> In one study, a group of Alzheimer's patients were given nicotine patches, while another received a placebo. Those with nicotine patches maintained their cognitive abilities longer and sometimes even recovered lost cognitive function.

> Contrary to popular opinion, the study showed that nicotine actually boosts the growth of new blood vessels.

> In 2006, Duke scientists found that people with depression who were treated with nicotine patches reported a decrease in their depressive feelings. The results were perhaps not surprising for a drug associated with imparting a "buzz." However, the research also showed a direct link between nicotine and an increase in the release of dopamine and serotonin, two vital neurotransmitters. A lack of dopamine or serotonin is a common cause of depression.

-- http://health.howstuffworks.com/wellness/drugs-alcohol/nicot...

again, there is much more on Google Scholar.

I find that nicotine's addictiveness is due to legality. That being said, I quit the various opiates much easier than cigarettes.

As a smoker, I wish it was illegal tomorrow. Then I could buy one or two smokes every now and then, but I would have to go well out of my way.

At $10 per cigarette, in a neighborhood where you're likely to get shot.

But they're illegal in order to keep us safe.

Right.

As someone that has smoked [1] I think legality is important - but it's also the relatively mild effects.

If you're getting frustrated at work, you can take a break, give yourself a quick "boost" by stopping for a cig, and then go back to work. Something that's not really possible with heroin, or marijuana or any other "drug" apart from caffeine.

[1] ten years on and I still don't say "ex-smoker" as one of the mental tricks to help me deal with it

EDIT formatting

You can also extract enough pure nicotine from a pack of cigarettes to kill a man, if you know how. It's not hard.

Nasty things.

Time for a cigarette break.

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