the same type of thinking that chess grandmasters had before computers and algorithms eventually caught up? I think it's just a matter of time, as long as the computer is not cheating, that computers and algorithms can beat most poker players.
Notice they tackle limit texas hold'em to keep the mathematics within reach. That's the time of crunching we're taking about. No-limit is impossible at this time. Not only will they need incredible computing power, but they also need the math to run it all, which remains unsolved. Could they use Sklansky's theory of Poker along with other optimal playing mathematics to win? Sure. But creating an unbeatable computer player? That is the incredible challenge.