That's certainly what I did. Firefox has improved immeasurably (at least for me) since about version 14, while Chrome has crept up in size. As a point of reference, if I open one tab in Chrome with Google Music and I let my computer idle for a minute, the various Chrome processes will sum up to between 800-1024MB of memory. You know how much Firefox with 8 tabs takes? 420MB.
Apparently people don't like this comment, but unlike some I do not possess scads and scads of RAM.