It shares the same designer as Magic (Richard Garfield), but is a Living Card Game rather than a Collectable Card Game. The difference being that in Magic you spend tons of money hoping for the random drop of particular rare cards or buy them individually from dealers. In A:NR, they release a new "data pack" about once a month and then have mini-expansions maybe once a year. It's more like a subscription model, but the net effect is that every card is worth the same as every other card. Still not a cheap hobby, but capped, at least (maybe about $175 to buy every card ever made up to today).
Anyways, someone built a RESTy API for it as well: http://netrunnercards.info/apidoc/en.html