For a long time, it seemed like everyone was using his form mail and web forum scripts.
It cured me of any inclination I might have had to actually learn and use Perl.
I wish I could recommend perl - CPAN modules generally really are amazingly high quality. But the mental cost of the perl programming model: no named params! arrayref vs array vs list! Contextual::Return! blessing scalars into objects! - that cost is just so friggin high that I can't imagine asking anyone to follow me there anymore.
But you get named parameters (and type checking of them!) for functions/methods through CPAN. And lots of other language extensions.
High flexibility in programming languages -- Perl isn't close to e.g. Lisp macros -- do have costs, of course. You need to use automatic tools, code reviews and coding standards. But you should do that anyway.
I really doubt the extra time/cognitive costs make for a noticeable extra burden, considering that you'll have to learn lots and lots of other stuff anyway.