There are hundreds of EWDs and I haven't seen a single one where Dijkstra would talk about making programming languages simple to make comprehension straightforward, this is something that modern programming "gurus" are more likely to say. The reason Dijkstra wants simple programming languages, and most EWDs are more or less about this, is because he wants to
prove theorems about programs, which is possible only with a simple language. Not only that, as I said he wants to
reduce program development to well defined transformations on a specification of a problem in the language of mathematical logic. His stance is very nicely summarized here:
http://en.wikipedia.org/wiki/The_Cruelty_of_Really_Teaching_...
You have to understand some mathematics and mathematical logic to really understand Dijkstra however, you cannot look at it from a pure software engineering background because you will only take away platitudes from what he says without actually understanding him. If you have some background you can read about his real technical ideas:
http://en.wikipedia.org/wiki/Program_derivation
http://en.wikipedia.org/wiki/Guarded_Command_Language
http://en.wikipedia.org/wiki/Predicate_transformer_semantics
This is the area Dijkstra worked most on during his research career. Those ideas actually go back centuries before anyone ever thought about structured programming. For hundreds of years there has been a fundamental debate ongoing on whether all kinds of reasoning can be reduced to some kind of calculi with well specified rules, which would be equivalent to being able to construct a (at least theoretical) machine for automating it. This is where computers come from, this goes back to Charles Babbage, to the works of Leibniz, Boole, Turing etc.
Dijkstra is in the same historical tradition. The program I understand Dijkstra has for Computer Science is similar to the program Hilbert had for mathematics with what is now called formalism, from which the work of Goedel and Turing sprung off. When programming was still mainly done by mathematicians this has been a lively research area, there were various systems of proving correctness invented, various ways of deriving programs, there has been a very heated debate on when proofs are needed and to what extent ordinary programmers have to master them etc. You can find loads of books and monographs written in the 70s and 80s about this. Now as far as research goes program derivation seems to be an almost dead topic, but there are still people today championing it in some alternative form. Richard Bird wrote a book called "Pearls of Functional Algorithm Design" where he derives algorithms using algebraical properties:
http://www.cs.ox.ac.uk/people/richard.bird/
Alexander Stepanov has been advocating something similar and wrote a book called "Elements of Programming":
http://www.elementsofprogramming.com/
https://www.youtube.com/watch?v=Ih9gpJga4Vc