What's a concrete example of (4) in this context that doesn't reduce trivially to (3)?
Note: Tay-Sachs is something that happens to Jews, and Jews are concentrated in New York.
Does the zip code connection satisfy your demand of "in this context"?
Though I think your Tay-Sachs example is one that arguably does not.
But I'm pretty sure the comment was referring to "Children in homes containing books display intelligence at elevated rates" not the overall article.