I remember doing the math in my undergraduate physics studies. Air molecules actually do not move very far when a vibration (ie. sounds) goes through them. Amazingly, high frequency sounds move air back and forth only a few angstroms.

I can't find a link describing the calculation. This link talks about how the change in pressure is equivalent to "140 molecules for every million molecules" http://www.silcom.com/~aludwig/musicand.htm

So there is no way you are going to create a bubble of vacuum!